Boutique Hotels in Panama City: Where Design Meets the Tropics

Find 8 boutique hotels in Panama City with unique design, pools, and ocean views. Compare rates and book now.

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1-8 out of 8
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8.7
Great8919 total reviews
our site & Booking.com
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1.5 km from City Centre400 m from Soho Mall
Conference RoomsSushi BarOutdoor Pool
  • 23 conference rooms for 1,300
  • Themed sushi bar lounge
  • 34-floor hotel with skyline views
From£ 81 /nightSelect
8.7
Great315 total reviews
our site & Booking.com
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2.1 km from City Centre300 m from Coastal Beltway
Pool BarSpa LoungeHot Tub
  • Award-winning spa with local ingredients
  • Ocean view pool bar for cocktails
  • Peacock Alley intimate cocktail lounge
From£ 94 /nightSelect
8.7
Great680 total reviews
our site & Booking.com
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5.1 km from City Centre400 m from Presidential Palace
Jazz BarOutdoor PoolFitness Centre
  • On-site jazz club with live music
  • Fusion cuisine and craft cocktails
  • Open-air pool and library
From£ 191 /nightSelect
8.8
Great919 total reviews
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2.5 km from City Centre1.2 km from Multicentro
Rooftop PoolCeviche Bar24-Hour Spa
  • Infinity pool overlooking Panama Bay
  • Live ceviche bar and waterfront dining
  • 24-hour spa with full services
From£ 105 /nightSelect
9.0
Perfect1154 total reviews
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1.6 km from City Centre700 m from Soho Mall
Panoramic SpaAward-winning RestaurantOutdoor Infinity Pool
  • Panamanian fusion award-winning restaurant
  • Spa with panoramic city views
  • 100-piece Latin American art collection
From£ 75 /nightSelect
8.5
Great4353 total reviews
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1.5 km from City Centre600 m from Parque Nacional Soberanía
Rooftop PoolFitness CentreBusiness Centre
  • Panoramic rooftop pool views
  • Mediterranean Gastro Bar on-site
  • Upscale El Cangrejo location
From£ 47 /nightSelect
8.1
Great7426 total reviews
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1.9 km from City Centre100 m from Multicentro
Rooftop RestaurantCasinoTurkish Bath
  • Rooftop dining with cityscape views
  • On-site casino and entertainment
  • Turkish bath spa treatments
From£ 54 /nightSelect
8.5
Great5001 total reviews
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1.9 km from City Centre100 m from Multicentro
Infinity PoolOn-site CasinoFull Spa
  • Direct mall and casino access
  • Sound of Your Stay music experience
  • Top-floor sky bar city views
From£ 84 /nightSelect

Panama City's boutique hotels blend contemporary style with local culture, offering more than just a place to sleep. Whether you seek skyline views from an infinity pool, historic charm in Casco Viejo, or oceanfront serenity along the bay, these properties deliver distinct character. Expect personalized service, thoughtful amenities like rooftop bars and spa facilities, and locations that put you close to the city's landmarks.

Budget-wise, boutique rates in Panama City typically range from $120 to $300 per night, depending on season and location. The most desired areas to stay include the financial district (for business and shopping), Casco Viejo (for colonial architecture and nightlife), and the waterfront near Cinta Costera. Top-rated options include Bristol Panama, a Registry Collection Hotel (superb score, 90) with a spa and sauna, and JW Marriott Panama (fabulous score, 88) offering infinity pools and ocean views. For a more intimate vibe, American Trade Hotel (score 87) sits in Casco Viejo with a jazz bar. Check for free cancellation and breakfast inclusions when booking.